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Intrathecal delivery of an adeno-associated viral vector serotype 9 (AAV9)-human SURF1 (hSURF1) has effectively corrected biochemical abnormalities in mouse models of SURF1 deficiency (107)

Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition

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J Pharm Sci 93:15371544 [DOI] [PubMed] [Google Scholar] Ebens A, Brose K, Leonardo ED, Hanson MG, Jr, Bladt F, Birchmeier C, Barres BA, Tessier-Lavigne M